Orson Scott Card's criticism of homosexuality and same-sex marriage prompted the organization GLAAD (Gay & Lesbian Alliance Against Defamation) to issue a critical statement questioning the morality of indirectly supporting Card's anti-LBGT activities.
In July 2013, the group Geeks Out launched a website campaign to boycott the film.
Mark Umbach, a public relations expert not associated with the film, commented: "there is a huge LGBT audience for science fiction, and it's going to be hard for those fans to separate Card’s comments from his work."
Andy Lewis and Borys Kit of The Hollywood Reporter wrote: "The new scrutiny of Card’s views could be a problem for the $110 million 'Ender’s Game' movie".
In response to the boycott, Card released a statement in July to Entertainment Weekly: "Ender’s Game is set more than a century in the future and has nothing to do with political issues that did not exist when the book was written in 1984. With the recent Supreme Court ruling, the gay marriage issue becomes moot. The Full Faith and Credit clause of the Constitution will, sooner or later, give legal force in every state to any marriage contract recognized by any other state. Now it will be interesting to see whether the victorious proponents of gay marriage will show tolerance toward those who disagreed with them when the issue was still in dispute."
Producer Roberto Orci responded in Entertainment Weekly in March that he was not aware of Card's views when he took on the film adaptation: "It didn't occur to me to do background checks on anybody." He said that "the movie should be judged on its message, not the personal beliefs of the original author, who had minimal involvement in the film". He also said that "If it's on the screen, then I think it's fair game."
Lionsgate Entertainment released a statement distancing themselves from Card, writing: "As proud longtime supporters of the LGBT community [...] we obviously do not agree with the personal views of Orson Scott Card and those of the National Organization for Marriage", and that Card's views are "completely irrelevant to the film adaptation".
Actor Harrison Ford does not consider Card's view an issue: "I am aware of his statements admitting that the question of gay marriage is a battle that he lost and he admits that he lost it. I think we all know that we’ve all won. That humanity has won. And I think that’s the end of the story."
Card has also received criticism for a controversial August 2013 essay that he described as "an experiment in fictional writing."
In it Card imagines a future, in which US President Barack Obama rules as a "Hitler- or Stalin-style dictator" with his own national police force of "young out-of-work urban men." Obama and his wife Michelle would amend the U.S. Constitution to allow presidents to remain in power for life, as in Nigeria, Zimbabwe, and Hitler's Germany.